Oral diacetylmorphine (heroin) yields greater morphine bioavailability than oral morphine: bioavailability related to dosage and prior opioid exposure
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چکیده
منابع مشابه
Relative Oral Bioavailability of Morphine and Naltrexone Derived From Crushed Morphine Sulfate and Naltrexone Hydrochloride Extended-Release Capsules Versus Intact
© 2010 Excerpta Medica Inc. All rights reserved. ABSTRACT Background: Morphine sulfate/sequestered naltrexone hydrochloride (HCl) (MS-sNT) extended-release fixed-dose combination capsules, approved by the US Food and Drug Administration (FDA) in August 2009 for chronic moderate to severe pain, contain extendedrelease morphine pellets with a sequestered core of the opioid antagonist naltrexone. ...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 2008
ISSN: 0306-5251,1365-2125
DOI: 10.1111/j.1365-2125.2008.03286.x